Gelclair® Bioadherent oral protective gel for mucisitis relief

Gelclair® is a bioadherent oral gel with a mechanical action which provides pain relief by adhering to the mucosal surface of the mouth, soothing oral lesions of various etiologies such as medication, disease, radiotherapy, chemotherapy, irritation due to oral surgery, ageing and traumatic ulcers caused by braces and ill-fitting dentures. Gelclair is also indicated for diffuse aphthous ulcers.

By creating a protective film that counteract the overstimulation of nerve endings Gelclair®

  • provides fast pain relief1
  • grants relevant pain reduction2 
  • reduces oral mucositis worsening3
  • improves the patient's ability to eat, drink, swallow, speak and sleep3,4
  • reduces the need to use parenteral feeding or opiate analgesics, compared to benzydamine which is a recommended therapeutic approach in the MASCC/ISOO guidelines4
  • reduces the total mouth bacterial amount at least in the first 6 hours after application5


1. MacKenzie et al, Support Care Cancer 2006; 14(6): 641(abstract 16-116).
2. Lindsay et al, Australian nursing Journal April 2009(16); 9: 30-33.
3. D'Andrea et al, Annals Oncol 2003; 14(supp4): 97(abstract N2).
4. Flook C et al. Support Care Cancer 2005.
5. Helsinn, Data on File.


Key Ingredients Gelclair® is a concentrated oral gel, classified as a "medical device", that contains three main ingredients.
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Mode of Action Gelclair®, once diluted with water rinsed around the mouth, forms a protective coating over the oral mucosa, which helps to soothe lesions and provide pain relief.
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Clinical studies In several clinical trials Gelclair® showed good results in term of reduction of pain and improvement of ability to eat and drink, reduction of the severity of mucositis and impact on quality of life (QoL) and acceptability of the product by patients.
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Safety Safety and tolerability profile of Gelclair®
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HELSINN This website is for Ex U.S. residents only Last Update: 19.02.2018
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