• Reasons for dose-reduction are pain management, nutrition and hydration improvement.
• "A significant number of patients develop mucositis to such severity as to require modification in their overall medical management" (NCI).
• 57% UK Palliative Care professionals employed dose reduction as a means of controlling the symptoms of oral mucositis.

Reference:
Trotti et al. Int J Radiat Oncol Biol Phys 2000;47:13-47.