Gelclair® vs. benzydamine in a randomised controlled study in patients with oral mucositis due to radical radiotherapy
|
|
- Gelclair® was shown to be at least as effective as benzydamine (recommended for the treatment of oral mucositis caused by radiotherapy by MASCC guidelines) in managing pain caused by oral mucositis.

- Gelclair® demonstrated significantly lower pain on application, possibly favouring the use of this medical device.
- Fewer patients in the Gelclair® group needed opiate medication; 20% with Gelclair® vs. 37.1% with benzydamine.
- No patients in the Gelclair® group needed artificial feeding with nasogastric tube; 0% with Gelclair® vs. 12.5% with benzydamine.
- Gelclair® can be considered a convenient and valid alternative to benzydamine for symptoms control and pain relief in patients undergoing anticancer therapies causing oral mucositis.
Reference: Flook C et al, Supportive Care in Cancer 2005; 13(6):443-4 (abs 15-098).
|
|
|
|